Oxidative imbalance in autoimmune liver disease: evaluation of oxidant-antioxidant status and ischemia-modified albumin

نویسندگان

چکیده

Objective: Current study evaluated the utility of total antioxidant status (TAS), oxidative stress index (OSI), oxidant (TOS), ischemia-modified albumin (IMA), and ratio (IMAR) as markers in autoimmune liver disease (AILD).
 Material Methods: The included a 66 AILD patients, 22 with hepatitis (AIH), 32 primary biliary cholangitis (PBC), 12 AIH/PBC overlap syndrome, 49 healthy controls. Serum TAS, TOS, IMA, (Alb), lactate dehydrogenase (LDH), alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine (ALT), bilirubin (TBil), direct (DBil), 25-hydroxyvitamin D (25[OH]D) were analyzed. OSI was calculated TOS/TAS IMAR derived from IMA Alb.
 Results: OSI, values found to be significantly higher group compared controls (p=0.004,

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ژورنال

عنوان ژورنال: Süleyman Demirel Üniversitesi T?p Fakültesi dergisi

سال: 2021

ISSN: ['1300-7416', '2602-2109']

DOI: https://doi.org/10.17343/sdutfd.738119